2020 Publications from the Department of Physiology and Biophysics
Publications 2020 publicationsAshraf S, Yilmaz G, Chen X, Harmancey R. Dietary fat and sugar differentially affect β-adrenergic stimulation of cardiac ERK and AKT pathways in C57BL/6 male mice subjected to high-calorie feeding. J Nutr. 2020 Jan 17. pii: nxz342. doi: 10.1093/jn/nxz342.da Silva AA, do Carmo JM, Li X, Wang Z, Mouton AJ, Hall JE. Role of Hyperinsulinemia and Insulin Resistance in Hypertension: Metabolic Syndrome Revisited. Can J Cardiol. 2020 May;36(5):671-682. doi: 10.1016/j.cjca.2020.02.066. Epub 2020 Feb 12.PMID: 32389340 Review.da Silva AA, do Carmo JM, Hall JE. CNS Regulation of Glucose Homeostasis: Role of the Leptin-Melanocortin System. Curr Diab Rep. 2020 May 26;20(7):29. doi: 10.1007/s11892-020-01311-1.PMID: 32451760 Review.Daseke MJ 2nd, Tenkorang-Impraim MAA, Ma Y, Chalise U, Konfrst SR, Garrett MR, DeLeon-Pennell KY, Lindsey ML. Exogenous IL-4 shuts off pro-inflammation in neutrophils while stimulating anti-inflammation in macrophages to induce neutrophil phagocytosis following myocardial infarction. J Mol Cell Cardiol. 2020 Jun 20;145:112-121. doi: 10.1016/j.yjmcc.2020.06.006. Online ahead of print.PMID: 32574573Deer EM, Welch B, Hernandez LL, Seeley RJ, Grayson BE. Nutrient and hormone composition of milk is altered in rodent dams post-bariatric surgery. J Dev Orig Health Dis. 2020 Feb;11(1):71-77. doi: 10.1017/S2040174419000424. Epub 2019 Aug 9.PMID: 31397254 Dent EL, Taylor EB, Sasser JM, Ryan MJ. Temporal hemodynamic changes in a female mouse model of systemic lupus erythematosus. Am J Physiol Renal Physiol. 2020 Mar 9. doi: 10.1152/ajprenal.00598.2019.Duncan JW, Younes ST, Hildebrandt E, Ryan MJ, Granger JP, Drummond HA. Tumor necrosis factor-α impairs cerebral blood flow in pregnant rats: role of vascular β-epithelial Na+ . Am J Physiol Heart Circ Physiol. 2020 Apr 1;318(4):H1018-H1027. doi: 10.1152/ajpheart.00744.2019. Epub 2020 Mar 13.PMID: 32167780 Duncan JW, Granger JP, Ryan MJ, Drummond HA. Interleukin-17 Reduces βENaC via MAPK Signaling in Vascular Smooth Muscle Cells.Int J Mol Sci. 2020 Apr 22;21(8):2953. doi: 10.3390/ijms21082953.PMID: 32331392 Eddy AC, Chapman H, Brown DT, George EM. Differential regulation of sFlt-1 splicing by U2AF65 and JMJD6 in placental-derived and endothelial cells. Biosci Rep. 2020 Feb 28;40(2). pii: BSR20193252. doi: 10.1042/BSR20193252.Eddy AC, Howell JA, Chapman H, Taylor E, Mahdi F, George EM, Bidwell GL 3rd. Biopolymer-delivered, maternall sequestered NF-kB (Nuclear Factor-kB) inhibitory peptide for treatment of preeclampsia. Hypertension. 2020 Jan;75(1):193-201. doi: 10.1161/HYPERTENSIONAHA.119.13368.Gordon DM, Neifer KL, Hamoud AA, Hawk CF, Nestor-Kalinoski AL, Miruzzi SA, Morran MP, Adeosun SO, Sarver JG, Erhardt PW, McCullumsmith RE, Stec DE, Hinds TD Jr. Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator-activated receptor α. J Biol Chem. 2020 May 13:jbc.RA120.013700. doi: 10.1074/jbc.RA120.013700. Online ahead of print. PMID: 32404366 Guo H, Xu D, Kuroki M, Lu Z, Xu X, Geurts A, Osborn JW, Chen Y. Kidney failure, arterial hypertension and left ventricular hypertrophy in rats with loss of function mutation of SOD3. Free Radic Biol Med. 2020 Jan 21. pii: S0891-5849(19)31433-9. doi: 10.1016/j.freeradbiomed.2020.01.023.Jenkins HN, Rivera-Gonzalez O, Gibert Y, Speed JS. Endothelin-1 in the pathophysiology of obesity and insulin resistance. Obes Rev. 2020 Jul 6. doi: 10.1111/obr.13086. Online ahead of print.PMID: 32627269 Johnson AC, Wu W, Attipoe EM, Sasser JM, Taylor EB, Showmaker KC, Kyle PB, Lindsey ML, Garrett MR. Loss of Arhgef11in the Dahl Salt-Sensitive Rat Protects Against Hypertension-Induced Renal Injury. Hypertension. 2020 Apr;75(4):1012-1024. doi: 10.1161/HYPERTENSIONAHA.119.14338. Epub 2020 Mar 9.PMID: 32148127Juraschek SP, Miller ER 3rd, Chang AR, Anderson CAM, Hall JE, Appel LJ. Effects of Sodium Reduction on Energy, Metabolism, Weight, Thirst, and Urine Volume: Results From the DASH (Dietary Approaches to Stop Hypertension)-Sodium Trial. Hypertension. 2020 Mar;75(3):723-729. doi: 10.1161/HYPERTENSIONAHA.119.13932.Kaminski AR, Moore ET, Daseke MJ 2nd, Valerio FM, Flynn ER, Lindsey ML. The compendium of matrix metalloproteinase expression in the left ventricle of mice following myocardial infarction. Am J Physiol Heart Circ Physiol.2020 Mar 1;318(3):H706-H714. doi: 10.1152/ajpheart.00679.Lu Q, Liu J, Li X, Sun X, Zhang J, Ren D, Tong N, Li J. Empagliflozin attenuates ischemia and reperfusion injury through LKB1/AMPK signaling pathway. Mol Cell Endocrinol. 2020 Feb 5;501:110642. doi: 10.1016/j.mce.2019.110642.Mannon EC, Ray SC, Ryan MJ, Sullivan JC. Does sex matter?: an update on the implementation of sex as a biological variable in research. Am J Physiol Renal Physiol. 2020 Feb 1;318(2):F329-F331. doi: 10.1152/ajprenal.00575.2019. Epub 2020 Jan 6. PMID: 31904284 No abstract available.Mouton AJ, Li X, Hall ME, Hall JE. Obesity, Hypertension, and Cardiac Dysfunction: Novel Roles of Immunometabolism in Macrophage Activation and Inflammation. Circ Res. 2020 Mar 13;126(6):789-806. doi: 10.1161/CIRCRESAHA.119.312321. Epub 2020 Mar 12.PMID: 32163341Naseem H, Dreixler J, Mueller A, Tung A, Dhir R, Chibber R, Fazal A, Granger JP, Bakrania BA, deMartelly V, Rana S, Shahul S. Antepartum Aspirin Administration Reduces Activin A and Cardiac Global Longitudinal Strain in Preeclamptic Women. J Am Heart Assoc. 2020 Jun 4:e015997. doi: 10.1161/JAHA.119.015997. Epub ahead of print. PMID: 32495688.Nemeth Z, Hildebrandt E, Ryan MJ, Granger JP, Drummond HA. Pressure-induced constriction of the middle cerebral artery is abolished in TrpC6 knockout mice. Am J Physiol Heart Circ Physiol. 2020 May 15. doi: 10.1152/ajpheart.00126.2020. Online ahead of print.PMID: 32412783Person JM, Welch BA, Spann RA, Harris KK, Pride Y, Tucci MA, Taylor EB, Grayson BE. Immuno-hematologic parameters following rodent spinal cord contusion are negatively influenced by high-fat diet consumption. J Neuroimmunol. 2020 Jun 15;343:577226. doi: 10.1016/j.jneuroim.2020.577226. Epub 2020 Mar 27.PMID: 32247229Rivera-Gonzalez OJ, Kasztan M, Johnston JG, Hyndman KA, Speed JS. Loss of endothelin type B receptor function improves insulin sensitivity in rats. Can J Physiol Pharmacol. 2020 Feb 21. doi: 10.1139/cjpp-2019-0666.Sehgal A, Alexander BT, Morrison JL, South AM. Fetal Growth Restriction and Hypertension in the Offspring: Mechanistic Links and Therapeutic Directions. J Pediatr. 2020 May 22:S0022-3476(20)30614-4. doi: 10.1016/j.jpeds.2020.05.028. Online ahead of print.PMID: 32450071 No abstract available.Sigmund CD, Carey RM, Appel LJ, Arnett DK, Bosworth HB, Cushman WC, Galis ZS, Green Parker M, Hall JE, Harrison DG, McDonough AA, Nicastro HL, Oparil S, Osborn JW, Raizada MK, Wright JD, Oh YS. Report of the National Heart, Lung, and Blood Institute Working Group on Hypertension: barriers to translation. Hypertension.2020 Feb 17:HYPERTENSIONAHA11913887. doi: 10.1161/HYPERTENSIONAHA.119.13887.Spann, RA, Grayson BE. Curbing Obesity from One Generation to Another: the Effects of Bariatric Surgery on the In Utero Environment and Beyond. Reprod Sci. 2020 Jun 23. doi: 10.1007/s43032-020-00221-7. Online ahead of print. PMID: 32578163 Review.Speed JS, Pruett WA, Lirette ST, Cook JJ, Phillips CL, Grayson BE. Cardiovascular risk factors following vertical sleeve gastrectomy in black americans compared with white americans. Obes Surg. 2020 Aug 22. doi: 10.1007/s11695-020-04938-x. Online ahead of print.PMID: 32827094Spradley FT, Ge Y, Granger JP, Chade AR. Utero-placental vascular remodeling during late gestation in Sprague-Dawley rats. Pregnancy Hypertens. 2020 Mar 3;20:36-43. doi: 10.1016/j.preghy.2020.02.007.Stec DE, Gordon DM, Nestor-Kalinoski AL, Donald MC, Mitchell ZL, Creeden JF, Hinds TD Jr. Biliverdin reductase A (BVRA) knockout in adipocytes induces hypertrophy and reduces mitochondria in white fate of obese mice. Biomolecules. 2020 Mar 2;10(3). pii: E387. doi: 10.3390/biom10030387.Surh YJ, Chung HT, Na HK, Dulak J, Stec DE. Progress in heme oxygenase research. Arch Biochem Biophys. 2020 Feb 24:108321. doi: 10.1016/j.abb.2020.108321. Van Tassell JC, Shimbo D, Hess R, Kittles R, Wilson JG, Jorde LB, Li M, Lange EM, Muntner P, Bress AP. Association of West African ancestry and blood pressure control among African Americans taking antihypertensive medication of the Jackson Heart Study. J Clin Hypertens (Greenwich).2020 Feb;22(2):157-166. doi: 10.1111/jch.13824.Wang S, Zhang H, Liu Y, Li L, Guo Y, Jiao F, Fang X, Jefferson JR, Li M, Gao W, Gonzalez-Fernandez E, Maranon RO, Pabbidi MR, Liu R, Alexander BT, Roman RJ, Fan F. Sex differences in the structure and function of rat middle cerebral arteries. Am J Physiol Heart Circ Physiol. 2020 May 1;318(5):H1219-H1232. doi: 10.1152/ajpheart.00722.2019. Epub 2020 Mar 27.PMID: 32216612Wang Z, do Carmo JM, da Silva AA, Fu Y, Hall JE. Mechanisms of synergistic interactions of diabetes and hypertension in chronic kidney disease: role of mitochondrial dysfunction and ER stress. Curr Hypertens Rep. 2020 Feb 3;22(2):15. doi: 10.1007/s11906-020-1016-x.Williams E, Chade AR. A Boolean model of microvascular rarefaction to predict treatment outcomes in renal disease. Sci Rep. 2020 Jan 16;10(1):440. doi: 10.1038/s41598-019-57386-8.Wilson JG, et al. National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group, O'Connor TD. De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2560-2569. doi: 10.1073/pnas.1902766117.Younes ST, Maeda KJ, Sasser J, Ryan MJ. The glucagon-like peptide 1 receptor agonist liraglutide attenuates placental ischemia-induced hypertension. Am J Physiol Heart Circ Physiol. 2020 Jan 1;318(1):H72-H77. doi: 10.1152/ajpheart.00486.Zhang D, Jin C, Obi IE, Rhoads MK, Soliman RH, Sedaka RS, Allan JM, Tao B, Speed JS, Pollock JS, Pollock DM. Loss of circadian gene Bmal1 in the collecting duct lowers blood pressure in male, but not female, mice. Am J Physiol Renal Physiol. 2020 Mar 1;318(3):F710-F719. doi: 10.1152/ajprenal.00364.2019.